Representative Publications:
 
  J.M. Thurman, B. Renner, K. Kunchithapautham, V.P. Ferreira, M.K. Pangburn, Z. Ablonczy, S. Tomlinson, V.M. Holers, and B. Rohrer. (2009) Oxidative Stress Renders Retinal Epithelial Cells Susceptible to Complement Mediated Injury. J. Biol. Chem. 284:16939-16947.
 
  V.P. Ferreira, A. Herbert, C. Cortes, K.A. Mckee, B. Blaum, S.T. Esswein , D. Uhrin, P.N. Barlow, M.K. Pangburn, and D. Kavanagh. (2009) The binding of factor H to a complex of the physiological polyanions and C3b on the cell surface is impaired in atypical hemolytic uremic syndrome. J. Immunol. 2009. 182:7009-7018.
 
 
M.K. Pangburn, N. Rawal, C. Cortes, V.P. Ferreira, and M. Atkinson. (2009) Polyanion-induced self association of complement factor H: Possible mechanism of host protection from an innate immune system. J. Immunol. 182:1061-1068.
 
 
M.K. Pangburn, V.P. Ferreira*, and C. Cortes*. (2008) Discrimination between Host and Pathogens by the Complement System. Vaccine. 26(Supplement 8):I15-I21. *Both authors contributed equally.
 
 
H.G. Hocking, A.P. Herbert, D. Kavanagh, D.C. Soares, V.P. Ferreira, M.K. Pangburn, D. Uhrín, and P.N. Barlow. (2008) Structure of the N-terminal region of complement factor H and the conformational implications of disease-linked sequence variations. J. Biol. Chem. 283:9475-9487.
 
 
V.P. Ferreira* and M.K. Pangburn. (2007) Factor H-mediated cell surface protection from complement is critical for the survival of PNH erythrocytes. Blood. 110:2190-2192. *Corresponding author.
 
 
A.P. Herbert, J.A. Deakin, C.Q. Schmidt, B. Blaum, C. Egan, V.P. Ferreira, M.K. Pangburn, M. Lyon, D. Uhrín, and P.N. Barlow. (2007) Structure shows glycosaminoglycan- and protein-recognition site in factor H is perturbed by age-related macular degeneration-linked SNP. J. Biol. Chem. 282:18960-18968.
 
 
V.P. Ferreira, A. Herbert, H. Hawkins, P. Barlow, and M.K. Pangburn. (2006) Critical role of the two C-terminal domains of factor H in regulating complement activation at cell surfaces. J. Immunol. 177:6308-6316.
 
  L. Aguilar, G. Ramírez, C. Valck, M.C. Molina, A. Rojas, W. Schwaeble, V. Ferreira, and A. Ferreira. (2005) F(ab’)2 antibody fragments against Trypanosoma cruzi calreticulin inhibit its interaction with the first component of human complement. Biological Res. 38:2-3.
 
  V. Ferreira, M.C. Molina, W. Schwaeble, D. Lemus, and A. Ferreira. (2005) Does Trypanosoma cruzi calreticulin modulate the complement system and angiogenesis? Trends in Parasitology. 21: 169-174.
 
 
M.C. Molina, V. Ferreira, C. Valck, G. Ramírez, L. Aguilar, A. Rojas, R. Billetta, D. Lemus, and A. Ferreira. (2005) An in vivo role for Trypanosoma cruzi calreticulin in antiangiogenesis. Molec. Biochem. Parasitol. 140:133-140.
 
  V. Ferreira, C. Valck, G. Sanchez, A. Gingras, S. Tzima, M.C. Molina, W. Schwaeble and A. Ferreira. (2004) The classical activation pathway of the human complement system is specifically inhibited by calreticulin from Trypanosoma cruzi. J. Immunol. 172: 3042-30500.
 
  V. Ferreira, M.C. Molina, C. Valck, A. Rojas, W. Schwaeble and A. Ferreira. (2004) Role of calreticulin from parasites in its interaction with vertebrate hosts. Mol. Immunol. 40: 1279-1291.
 
  A. Aguirre, A. Escobar, V. Ferreira, M.C. Molina, A. Ferreira and J.C. Aguillón. (2003) An anti-human recombinant tumor necrosis factor alpha (TNF?) monoclonal antibody recognizes an epitope in feline TNF?. Vet. Res. 34:177-184.
 
  V. Ferreira, M.C. Molina, C. Valck, A. Rojas and A. Ferreira. (2002) Parasite calreticulin: possible roles in the parasite / host interface. Inmunología (Madrid). 21: 156-168.
 
  J.C. Aguillón, L. Ferreira, V. Ferreira, A. Escobar, A. Aguirre, M.C. Molina and A. Ferreira. (2001) Assessment of inter-individual variations in the daily production of human tumor necrosis factor in an ex vivo blood culture assay. Eur. Cytokine Net. 12: 105-110.
 
  A. Moreno, R. Rodriguez, G. Oliveira, V. Ferreira, R. Nussenzweig, R. Moya-Castro, M. Calvo-Calle and E. Nardin. (1999) Pre-clinical evaluation of a synthetic Plasmodium falciparum MAP malaria vaccine in Aotus monkeys and mice. Vaccine. 18: 89-99.
 
  J.C. Aguillón, V. Ferreira, E. Núñez, L. Paredes, M.C Molina, A. Colombo, T. Hermosilla and A. Ferreira. (1996) Immunomodulation of LPS ability to induce local Shwartzman reaction. Scand. J. Immunol. 44: 551-555.
 
  Book Chapters:
 
 
V. Ferreira and A. Ferreira. (2005) “Sistema del Complemento” (The Complement System). Book chapter in: Inmunología Básica y Clínica (Basic and Clinical Immunology). Mediterraneo Editorial. Pgs. 130-150.