Representative Publications:
 
  Mai, J., S.G. Sawicki, R. Gorchakov, I. Frolov, and D.L. Sawicki, 2008. Replication impact of continuous minus strand synthesis by alphavirus replication complexes containing P23 nonstructural polyproteins. J. Virology, submitted.
 
  Lutta, D. Sawicki, S. Sawicki Merits and Ahola, 2008. Molecular defects in Semliki Forest virus temperature sensitive mutants ts10 and ts14 mapping to nsP1. J. Virology 82:9236-9244.
 
 
Gorchakov, R., Frolova, E., Sawicki, S., Atasheva, S., Sawicki, D., and Frolov, I. (2008) A new role of ns polyprotein cleavage in Sindbis virus replication. J. Virology, 82:6218-6231.
 
 
Sawicki, S.G., Sawicki, D.L., Siddell, S.G. (2007) A contemporary view of coronavirus transcription. J Virol. 81(1): 20-29. Epub 2006 Aug 23.
 
  S. Sawicki, D. Sawicki and S. Siddell. 2007. Invited Minireview: A contemporary view of coronavirus transcription. J. Virology June 2006.
 
 
Sawicki, D.L., Perri, S., Polo, J.M., Sawicki, S.G. (2006) Role for nsP2 proteins in the cessation of alphavirus minus-strand synthesis by host cells. J. Virol. Jan; 80(1):360-376.
 
 
Mahboubi, K., Witman-Jones, T., Adamus, J.E., Letsinger, J.T., Whitehouse, D., Moorman, A.R., Sawicki, D., Bergenham, N., Ross, S.A. (2006) Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74. Biochem Biophys Res Commun. Feb 10; 340(2): 482-490.
 
 
Sawicki, D.L., Perri, S., Polo, J.M., and Sawicki, S.G. (2006) Role for nsP2 proteins in the cessation of alphavirus minus strand synthesis by host cells. J. Virol. 80(1):360-371.
 
  Sawicki, S., Sawicki, D., Younker, D., Meyer, Y. Thiel, V., Stokes, H. and Siddell, S. 2005. Functional and genetic analysis of coronavirus replicase proteins. PloS pathogens 1(4): e39.
 
 
Sawicki, S., and Sawicki, D.L. (2005) Coronavirus Transcription: A Perspective, in “Coronavirus Replication and Reverse Genetics”, (ed) L. Enjuanes. Springer Verlag. pp 31-55.
 
 
Dé, I., Fata, C.L., Sawicki, S.G., and Sawicki, D.L. (2003) Functional analysis of nsP3 phosphoprotein mutants of Sindbis Virus. J. Virol. 77(24):13106-13116.
 
 
Sawicki, D.L., Silverman, R.H., Williams, B.R., and Sawicki, S.G. (2003) Alphavirus Minus Strand Synthesis and Persistence in Mouse Embryo Fibroblasts Derived from Mice Lacking RNase L and PKR. J. Virol. 77: 1801-1811.
 
 
Fata, C.L., Sawicki, S.G., and Sawicki, D.L. (2002) Modification of Asn374 of nsP1 Suppresses
A Sindbis nsP4 Minus Strand Polymerase Mutant. J. Virol. 76: 8641-8649.
 
 
Fata, C.L., Sawicki, S.G., and Sawicki, D.L. (2002) Minus Strand RNA Synthesis: Identification of a Role for Arg183 of the nsP4 Polymerase. J. Virol. 76: 8632-8640.
 
 
Sawicki, D., Wang, T., and Sawicki S. (2001) Mouse hepatitis virus replicative- and transcriptive intermediate & replicative and transcriptive form RNA: Characterization of the seven species. J. Gen. Virol. 82: 385-396.
 
  Sawicki, D., and S. Sawicki. 2000. Chromatography of Mouse Hepatitis Virus Replicative Intermediate and Replicative Form RNA. Proceedings, Nidovirus International Symposium. Plenum Press, NY.
 
  Siddell, S., D. Sawicki, Y. Meyer, V. Thiel and S. Sawicki. 2000. Identification of mutations responsible for the phenotype of three MHV RNA-negative mutants. Proceedings, Nidovirus International Symposium. Plenum Press, NY.
 
 
Sawicki, S.G. and Sawicki, D.L. (1998) A New Model for Coronavirus Transcription. Advances in Experimental Medicine, 440: 215-220.
 
 
Sawicki, D.L and Sawicki, S.G. (1998) Role of the Nonstructural Polyproteins in Alphavirus Transcription. Advances in Experimental Medicine, 440: 187-195.
 
  Suopanki, J., D.L. Sawicki, S.G. Sawicki, and L. Kaariainen. 1998. Regulation of alphavirus 26S mRNA transcription by replicase component nsP2. J. General Virology, 79:309-319.
 
  Dé, I., S.G. Sawicki and D.L. Sawicki. 1996. Sindbis RNA-negative mutants that fail to convert from minus-strand to plus-strand RNA synthesis: I. Role of the nsP2 protein. J. Virology, 70:2706-2719.
 
  Sawicki, S.G., and D.L. Sawicki. 1995. Coronaviruses use discontinuous extension for synthesis of subgenome-length negative strands. pp 499-506. In, P.J. Talbot and G.A. Levy (eds), "Corona- and Related Viruses," Plenum Press, N.Y.
 
  Sawicki, D.L., and S.G. Sawicki. 1994. The functions of the alphavirus nonstructural proteins in positive and negative strand RNA synthesis and the role of polyproteins in formation of viral replication complexes. Archives of Virology, Suppl. 9: 393-405.
 
  Wang, Y. F., S. G. Sawicki, and D. L. Sawicki. 1994. Alphavirus nsP3 functions to form a replication complex transcribing negative strand RNA. J. Virology, 68: 6466-6475.
 
  Sawicki, D. L., and S.G. Sawicki. 1993. A second nonstructural protein functions in the regulation of alphavirus negative-strand RNA synthesis. J. Virology, 67: 3605-3610.
 
  Wang, Y. F., S. G. Sawicki, and D. L. Sawicki. 1991. Characterization of a single amino acid substitution in nsP1 that confers temperature-sensitive negative strand synthesis. J. Virology, 65: 985-988.
 
  Barton, D. J., D. L. Sawicki, and S. G. Sawicki. 1991. Solubilization and immunoprecipitation of alphavirus replication complexes. J. Virology, 65: 1496-1506.
 
  Barton, D. J., D. L. Sawicki, and S. G. Sawicki. 1990. Association of alphavirus replication with the cytoskeletal framework and transcription in vitro in the absence of membranes. In, Brinton, M.A. and F.X. Heinz. (eds). "New Aspects of Positive Strand RNA Viruses." Chapter 12. ASM Press, Washington, D.C.
 
  Sawicki, S. G. and D. L. Sawicki. 1990. Coronavirus transcription: subgenomic mouse hepatitis virus replicative intermediates function in RNA synthesis. J. Virology, 64:1050-1056.
 
  Sawicki, D.L., D. Barkheimer, S. G. Sawicki, C.M. Rice, and S. Schlesinger. 1990. Temperature sensitive shut-off of alphavirus minus strand RNA synthesis maps to a viral nonstructural protein, nsP4. Virology 174:43-52.
 
  Barton, D.J., S.G. Sawicki and D.L. Sawicki. 1988. Demonstration in vitro of temperature sensitive elongation of RNA in Sindbis virus mutant ts6. J. Virology, 62:, 3597-3602.
 
  Sawicki, D.L. and S.G. Sawicki. 1987. Alphavirus plus strand and minus strand RNA synthesis. In: M. Brinton and R. Rueckert (eds.),"Positive Strand RNA Viruses," Alan R. Liss, New York, New York. pp 251-259.